Aim: Occupational dermatoses are common and often affect young workers at the beginning of their careers. This project aimed at the development of primary prevention measures for specific target groups, their implementation with trainees in jobs involving a risk of skin damage, and their evaluation. Method: A 60-minute lesson on occupational skin hazards and skin protection measures was developed and implemented with 133 apprentices training at the Robert Bosch company in Ansbach. For the evaluation, the participants filled in a questionnaire prior to and 4 weeks after the training. Besides asking about facts communicated in the lesson, the questions dealt with actual skin hazards at the workplace and currently applied skin protection measures. Results: 120 questionnaires were evaluated. 44% of participants reported daily workplace hazardous skin exposure for at least 2 hours. 4 weeks after the training, 77% of apprentices showed an increase in knowledge, especially concerning skin protection and skin cleansing, and over 40% of participants had improved their skin protection measures. The lesson was rated “very good” or “good” by 86% of participants. 90% of trainees considered schooling on this subject during apprenticeship important. Conclusions: As a result of the training, not only knowledge about skin protection measures was increased, but also behavioural changes were achieved. We suggest the universal implementation of such training measures in companies with jobs involving a risk of skin damage.